Know Before You Mix
Fish oil + Vitamin E? Calcium + Iron? Our supplement interaction checker flags conflicts, timing issues, and redundancies before they become problems.
Learn how we detect interactions
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Documented interactions
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Check how your supplements and medications actually interact
PharmaGuide is an AI-powered supplement interaction checker that analyzes drug–drug interactions, drug–supplement conflicts, supplement-to-supplement interactions, and product quality using published clinical research and clinician-reviewed educational guidance — the supplement safety checker built so you know what's safe, what to avoid, and what to discuss with your provider.
The only app that checks drug–drug,
drug–supplement, and
supplement–supplement interactions — in one
scan.
Educational content reviewed by
Dr. Pham L., PharmD &
Miriam D., NP
HIPAA-Aligned Design
Research-Backed
200K+ Interactions
Documented interaction pairs in our database (drug–supplement +
supplement–supplement)
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Where our supplement interaction data comes from — and how it's verified.
Review Process
Every interaction is verified by licensed pharmacists with clinical oversight — not just algorithms.
Update Cadence
Continuous monitoring of FDA alerts and new research. Quarterly systematic reviews. See our full methodology →
Built by Engineers. Verified by Licensed Clinicians.
Interaction data is reviewed by licensed pharmacists, physicians, and clinical researchers before publication.
How We Verify Interaction Data
FDA & NIH Research
Pharmacist Review
Clinical Validation
Ongoing Updates
Engineering Team
Software engineers focused on accuracy, security, and privacy-first health data systems.
Sean C.
Software Engineer • 10 years
Thomas Y.
Data Engineer • 8 years
Medical Advisory Board
Licensed healthcare professionals who review interaction data for clinical accuracy.
Dr. Pham L., PharmD
Clinical Pharmacist • 15+ years
Miriam D., NP
Nurse Practitioner • 12 years
How clinician testers pressure-tested PharmaGuide
Six clinicians across four specialties used PharmaGuide in prelaunch accuracy reviews to pressure-test interaction logic, citations, and wording. The tool is built to support clinical judgment, not replace it.
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Clinician Testers
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Practice Areas
4.9
Avg. Accuracy Review Score
Testing focused on whether interaction flags, citations, and wording were clinically reasonable and easy to review. These reviewers are not replacing individual medical judgment or providing patient-specific care through PharmaGuide.
I used PharmaGuide to review complex medication and supplement stacks during testing. It surfaced interaction checks I would have verified manually and gave me a faster starting point — without pretending to replace clinical judgment.
In primary care, I get supplement questions constantly and usually have to piece answers together across multiple references. PharmaGuide made the first-pass review faster and easier to explain because everything was already organized in one place.
For higher-risk patients, I care less about hype and more about what needs to be double-checked. PharmaGuide worked well as a screening layer — it flagged the right interactions without overstepping clinical judgment.
Everything you need to check supplement interactions safely
Clinical-grade tools that work together to protect your health — from drug-supplement conflict detection to supplement quality scoring.
Scan Any Bottle
Point your camera at any supplement. Our barcode scanner recognizes 210,000+ products and instantly checks for dangerous interactions.
How scanning works
<1s
Scan time
Ask the AI Pharmacist (Educational Guidance)
Get answers about supplement safety backed by peer-reviewed research—reviewed by licensed pharmacists. No sales pitches, just clear guidance.
Meet our AI
24/7
Always available
Personalized to You
Your age, health conditions, and current medications matter. Get interaction checks tailored specifically to your health profile.
Why personalization matters
Tailored
Just for you
Your Data Stays Yours
Health data never leaves your phone. Local processing, no cloud sync, HIPAA-aligned design. Read our privacy commitment.
Our privacy promise
HIPAA
Aligned Design
When does PharmaGuide actually matter?
Every day, millions of people take supplements without checking what could go wrong. Here's what PharmaGuide catches.
You
are 14 weeks pregnant and still taking your pre-pregnancy supplement
stack.
PG
Flags high-dose vitamin A and herbal ingredients contraindicated in
pregnancy. Recommends prenatal-safe alternatives.
You
take an SSRI for anxiety and add St. John's Wort for mood support.
PG
Serotonin syndrome risk detected. Two serotonergic agents combined —
verdict: UNSAFE without provider clearance.
You
take levothyroxine for thyroid and calcium + iron with breakfast.
PG
Both reduce thyroid medication absorption by up to 60%. Recommends
4-hour spacing window.
You
take Warfarin and a friend recommends turmeric for joint pain.
PG
Curcumin inhibits platelet aggregation and interacts with Warfarin —
verdict: UNSAFE without medical guidance.
You
pick a 4.8-star supplement on Amazon with 12,000 reviews.
PG
No third-party testing found. Contains two additives flagged for
long-term concern. PG Score: 41/100.
You
buy a weight-loss supplement promoted by an Instagram influencer.
PG
Product matched to active FDA recall. Contains undeclared sibutramine
— a banned stimulant. Verdict: BLOCKED.
You
give your 8-year-old a gummy multivitamin with artificial dyes.
PG
Detects Red 40 and Yellow 6 — additives linked to behavioral concerns
in children. Suggests cleaner alternatives.
You
re-order your usual magnesium and don't notice the formula changed.
PG
Detects switch from magnesium glycinate to oxide — 4x lower
absorption. Flags the downgrade before you take it.
The supplement interaction most people don't know about.
It happens more often than you think.
Sarah takes calcium and vitamin D every morning for bone health. Her doctor prescribed levothyroxine for hypothyroidism. She takes them together with breakfast — both from trusted sources.
Calcium can reduce levothyroxine absorption by up to 60% when taken at the same time. NIH confirms this interaction. After a month, her thyroid levels weren't improving — and neither she nor her doctor connected the dots.
PharmaGuide flags interactions like this
Based on peer-reviewed clinical literature reviewed by pharmacists and physicians.
Every day, thousands of people visit the ER due to adverse drug events, including known drug interactions.
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ER visits per day in the U.S.
Information is your first line of defense
Who It's For
Who PharmaGuide Is For — From Optimization to Medication Safety
PharmaGuide adapts to your health journey—whether you're optimizing supplements or managing medications.
The Optimizer
You track macros, sleep, and workouts. PharmaGuide reveals which supplements work together and which cancel each other out. Ideal for supplement stack optimization and interaction checking.
Stack Optimization Learn about supplement interactionsThe Chronic Manager
Managing diabetes, hypertension, or multiple medications? Get a clear picture of how your supplements interact with your prescriptions. Essential for drug–supplement interaction checking and medication safety.
Safety Awareness Learn about drug–supplement conflictsThe Athlete
Competing clean means knowing what's in your supplements. PharmaGuide checks USP, NSF, ConsumerLab, and IFOS certifications — and screens for WADA-prohibited substances. Designed for competitive athletes who need banned substance screening and sport certification verification.
Sport Certified Learn about sport certificationsThe Parent
You childproof everything and read every label. Bring that same care to your family's supplements—for kids and adults alike. Perfect for family supplement safety and multi-generational health management.
Family Protection Learn about supplement safetyHow PharmaGuide Works
An educational supplement interaction checker built on published clinical research. Four simple steps to check supplement interactions, quality, and safety.
01
Scan Your Supplements
Scan any supplement barcode or label. We match against 210,000+ products in our verified database. Supports barcode scanning and manual search for supplement identification.
Your Data Stays Private
02
Get a Supplement Quality Score
Receive a 0-100 quality rating based on purity, potency, safety, and bioavailability. Quality scores are derived from third-party testing and clinical research data.
Research-Backed
03
Check Supplement & Drug Interactions
Our analysis identifies documented supplement and drug interactions from clinical literature to discuss with your provider. Interaction data is sourced from FDA databases and peer-reviewed research.
Stay Informed
04
Review & Take Action
Generate a doctor-ready report, get guidance from our AI assistant, or simply feel more confident about your choices. Reports can be shared with healthcare providers for informed discussions.
You're in ControlQuestions About Our Supplement Interaction Checker
Everything you need to know about PharmaGuide and how it keeps you safe.
Interaction information is provided for educational purposes only and is based on published research. Individual responses may vary.
Can't find your answer? Check our blog or reach out at info@pharmaguide.io
Beta Access
Be the first to understand what's really in your stack
Early access rolls out in limited waves starting in Q2 2026. Sign up for product updates, health insights, and first access before public launch.
Pressure-tested by 6 clinicians across 4 specialties to review interaction logic, citations, and wording. Built to support clinical judgment, not replace it.
- Early access before public launch
- Early supporter pricing benefits
- Priority support & feedback channel
Want to learn more first? See how PharmaGuide works →
Beta access rolls out in limited waves starting in Q2 2026.
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Questions? Reach us at info@pharmaguide.io
Page last reviewed: March 2026 by Dr. Pham L., PharmD